As you know, Windows Server 2016 will have Defender installed by default. Here could be a problem as we have to do some exclusions and we don’t look how the Defender is configured by default.
Microsoft published one great post where you can see what are exceptions in Defender for each server role and of course this is a good start also to configure your own antivirus software. Be careful, because it is true that antivirus software can protect you, but a misconfigured one can make also damages.
About me
I am working in IT for more than 10 years, concerning most of my time with small companies. A result of this work is a good knowledge of problems and products used in that companies, like Windows Small Business Server, System Center Essentials, Windows OS ecc.
I lead a Slovenian SBS Community on Microsoft, I am Microsft MVP for Cloud and Datacenter (2012 – 2018).
In my privat life I like listen to rock music, archery and constructing biiig houses with Lego cubes – of course with my son!